I dip my SPS with Coral Rx while I'm acclimating them to my water. I take out half of the water they came in, add the Coral Rx, then dump the amount of water I took out back in with tank water. and let sit for 15 mins. I don't drip. I would think they would definitly stress without water acclimation.
And as I've experienced before, sometimes the STN/RTN happens days or weeks after the initial stress event happens.